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VA Technical Reference Model v 26.1

HL7 V2 Laboratory Orders from EHR (LOI)
HL7 V2 Laboratory Orders from EHR (LOI) Standard or Specification

General Information

Technologies must be operated and maintained in accordance with Federal and Department security and privacy policies and guidelines. More information on the proper use of the TRM can be found on the TRM Proper Use Tab/Section.

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Description: The Laboratory Orders Interface Initiative focuses on identifying the requirements, specifications and standards, and on providing the implementation guidance for electronic ordering of laboratory tests in the US Realm. The scope of the Laboratory Orders Interface Use Case includes requirements to enable a particular implementation of Electronic Health Record System (EHR-S) to use standardized structured data in a defined inter-organizational laboratory transaction. The Use Case requirements are directed at laboratory test orders between an Ambulatory Provider’s EHR-S and a Laboratory’s Laboratory Information System (LIS). Future versions of this guide may harmonize with existing guides to extend interoperability of laboratory results across care settings, e.g., acute care.

The “HL7 Version 2.5.1 Implementation Guide: S&I Framework Laboratory Orders from EHR, Edition 5 - US Realm”, referred to as the Laboratory Orders Interface Implementation Guide (LOI IG) is a companion guide to the “Version 2.5.1 Implementation Guide; Orders and Observations; Interoperable Laboratory Result Reporting to EHR (US Realm), Release 1 STU Release 4” referred to as the Laboratory Result Interface IG (LRI IG) and the “HL7 Version 2 Implementation Guide: Laboratory Test Compendium Framework, Release 2 DSTU 4” referred to as the electronic Directory of Service IG (eDOS IG).
Technology/Standard Usage Requirements: Users must ensure their use of this technology/standard is consistent with VA policies and standards, including, but not limited to, VA Handbooks 6102 and 6500; VA Directives 6004, 6513, and 6517; and National Institute of Standards and Technology (NIST) standards, including Federal Information Processing Standards (FIPS). Users must ensure sensitive data is properly protected in compliance with all VA regulations. Prior to use of this technology, users should check with their supervisor, Information System Security Officer (ISSO), Facility Chief Information Officer (CIO), or local Office of Information and Technology (OI&T) representative to ensure that all actions are consistent with current VA policies and procedures prior to implementation.
Section 508 Information:
Decision: View Decisions
Decision Source: TRM Mgmt Group
Decision Process: One-VA TRM v25.11
Decision Date: 11/19/2025 at 17:18:29 UTC
Aliases: "HL7 Version 2.5.1 Implementation Guide: Laboratory Orders from EHR (LOI) Edition 5 - US Realm", LOI IG, Laboratory Order Interface, LOI, Laboratory Orders (LOI) (US) (V2)
Introduced By: TRM Request
Standards Body: HL7
Cage Code: 3ZPX5
- The information contained on this page is accurate as of the Decision Date (11/19/2025 at 17:18:29 UTC).